AOD9604 [5mg]

The primary body of preclinical work has focused on adipose tissue metabolism, fat oxidation, and beta-adrenergic signaling in rodent obesity models. Research led by Ng and colleagues at Monash University, and later extended by Heffernan and co-investigators, examined lipid metabolism in obese Zucker rats and genetically modified beta₃-adrenergic receptor knock-out mice. A separate line of research examined AOD9604 in cartilage biology models including intra-articular administration. All findings referenced here derive from preclinical models and have not been validated in controlled human clinical trials.